Postdoctoral Research Fellow - Epigenetic and Circadian Mechanisms of Striated Muscle Biology
Cincinnati Children's Hospital Medical Center
Location: Cincinnati, Ohio
Academic / Research
Internal Number: 140533
Expected Starting Salary Range: - salaries align with the NIH extramural postdoc payscale
A postdoctoral Research Fellow position is available immediately in Dr. Mattia Quattrocelli's laboratory. The Quattrocelli lab investigates the interplay between metabolic, circadian, and epigenetic mechanisms that govern striated muscle function, cardiovascular health, and exercise tolerance. Our multidisciplinary research interests span pharmacology and physiology of cardiovascular disease and skeletal muscle disorders, addressing the unmet needs of complex diseases like aging, diabetes, heart failure and muscle wasting. We are also interested in linking functional muscle/cardiac outcomes to the crosstalk with non-myocyte cells like adipocytes, hepatocytes, and immune cells. We use complementary combinations of transgenic mice, omics datasets, metabolic assays, circadian modulation, in vitro/ex vivo isotope tracing, primary cell lines and human induced pluripotent stem cells. The laboratory is committed to support postdoctoral fellows in any career aspirations (academia, industry, etc.).
MAJOR DUTIES AND RESPONSIBILITIES:
Design, execute, and record laboratory experiments, and analyze the data.
Research and improve current methods and evaluate innovative techniques. Implement this knowledge in the Division/Department.
Present research at laboratory meetings, journal clubs, seminars, and meetings.
Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grants.
Maintain currency in field through continuing education, literature, and seminars.
Attend required Cincinnati Children's training sessions and ensure regulatory compliance with all policies and procedures.
Perform other duties as assigned.
Ph.D. in related discipline, MD, or equivalent required.
Recent Ph.D. candidates with research experience in muscle and/or heart physiology, metabolism, epigenetics, circadian rhythm and/or immunology are encouraged to apply. The ideal candidate will have a strong interest in mechanistic-to-translational physiology with a keen appreciation of in vivo versus in vitro study relevance. They will work well in teams as well as independently, proactively advance their project significance and career development with the help of a supportive mentorship, and be organized, self-motivated and hardworking.
REQUIRED SKILLS: Excellent written, verbal, and interpersonal communication skills. Demonstrate attention to detail, strong organizational skills, supervisory ability, and an innovative approach to experimental design. Computer literate and working knowledge of software applications (word processing, spreadsheet, and database). Analytical ability sufficient to compare data; mathematical ability sufficient to perform algebraic calculations and statistical analysis. Ability to synthesize information and to create and deal with new situations by applying past experiences. Expressed willingness to teach others and share results. Capable of meeting time demands necessary to execute experiments.
Cincinnati Children's is proud to be an Equal Opportunity Employer that values and treasures Diversity, Equity, and Inclusion. We are committed to creating an environment of dignity and respect for all our employees, patients, and families (EEO/AA).
About Cincinnati Children's Hospital Medical Center
At Cincinnati Children’s, we come to work with one goal: to make children’s health better. We believe in a team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better, and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children’s.